Summary: The immune-genetic changes that occur in cancer patients experiencing hyperprogressive disease (HPD) during combined immunotherapy are unclear. In this study. HPD patients with pre- and post-HPD samples and non-HPD patients with solid tumors were molecularly characterized by genetic and tumor immune microenvironment (TiME) analyses of paired samples by whole-exome sequencing.... https://www.bekindtopets.com/mega-deal-Chocolate-Puddles-the-Platypus-180g-Gourmet-brands-super-choice/