BackgroundFabry disease (FD) is caused by a deficiency of the lysosomal enzyme alpha-galactosidase A (GLA) resulting in the accumulation of globotriaosylsphingosine (Gb3) in a variety of tissues. While GLA deficiency was always considered as the fulcrum of the disease. recent attention shifted towards studying the mechanisms through which Gb3 accumulation in vascular cells leads to en... https://parisnaturalfoodes.shop/product-category/org-pitted-dates/